With RayStation®*, your reirradiation workflow is simplified. Now with Plan + Prior treatment dose and optimization based on EQD2 for proton and light ions, the dose is automatically deformed to the new treatment image.
Reirradiation support
With the upcoming RayStation v2026*, RaySearch introduces enhanced support for reirradiation planning and evaluation. The new framework includes cumulative dose assessment based on deformable image registration and equieffective dose in 2 Gy fractions (EQD2). The framework enables ROI‑specific EQD2 parameters, including the modeling of partial tissue recovery between treatment courses.
Because reirradiation is fundamentally constrained by cumulative dose to organs at risk (OARs), particle therapy is particularly well suited for these scenarios. Its ability to reduce unnecessary dose to previously irradiated tissues helps mitigate the risk of severe toxicity, even in complex reirradiation cases. Reflecting this, RayStation supports reirradiation planning across modalities – including all currently supported delivery techniques for proton, helium, and carbon ion therapy – regardless of the modality used in prior treatments.
To further strengthen particle therapy in reirradiation, RayStation enables robust optimization of cumulative EQD2, allowing direct consideration of prior OAR doses in the optimization process. This can be combined with conventional robust optimization for the reirradiation target, accounting only for the dose contribution from the current plan. Together, these capabilities support a balanced and clinically relevant trade‑off between cumulative OAR doses and target coverage.
*Subject to regulatory clearance in some markets. RayStation v2026 is not available for use or sale in the USA or Canada. Functionality available can differ depending on scope of regulatory clearance, refer to your local vendor for available functionality in your country.
New Webinar Series!
RAYSEARCH WEBINARS: ADVANCING REIRRADIATION SERIES
🔥Episode 1: Reirradiation in RayStation®: Planning with cumulative EQD2 in 3D**
Together with experts from RaySearch and Leeds Teaching Hospitals NHS Trust, we explored how the upcoming RayStation®* version supports cumulative EQD2 evaluation and optimization for reirradiation planning**, including clinical case demonstrations** and a lively Q&A session.
📽️ For those who were unable to attend, you can watch the recording here.
📖 We have also compiled all questions raised during the webinar and their corresponding answers, which you can access here.
🔥 Stay tuned for the next episode in the series!
Reirradiation Challenges and Solutions Stina Svensson - RaySearch Webinars ASTRO 2025 Edition
This webinar explores the advancements and challenges in re-irradiation planning within radiotherapy, highlighting the increasing need for retreatments due to improved patient outcomes and more precise treatment options. The session covers technical complexities such as dose accumulation, deformable image registration, and the integration of biological planning tools, with insights into ongoing research collaborations and upcoming software releases aimed at enhancing clinical practice.